Found 38 matching trials
Safety, Tolerability and Efficacy of PfSPZ Vaccine Against Heterologous CHMI in US Malaria naïve Adults PHASE1 This is a randomized, double blind, placebo-controlled, single site, trial ...
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Fred Hutchinson Cancer Research Center
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Safety and Immunogenicity in Age De-Escalation of PfSPZ Vaccine in Tanzanian Adults, Children, and Infants PHASE1 The present trial will evaluate safety and tolerability as well as the vacc...
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Bagamoyo Research and Training center of the Ifakara Health Institute
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PfSPZ Challenge in Healthy Malaria-Naïve Adults in the United States PHASE1 This phase I trial of the replication-intact PfSPZ Challenge vaccine given ...
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Kaiser Permanente Washington Health Research Institute - Vaccines and Infectious Diseases
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Safety and Immunogenicity of Direct Venous Inoculation of a Radiation-attenuated PfSPZ Vaccine in Equatoguinean Adults PHASE1 This is a single center, randomized, placebo-controlled, double-blind trial...
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La Paz Medical Center
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Study to Evaluate Safety, Immunogenicity and Efficacy of PfSPZ Vaccine in HIV Negative and HIV Positive Tanzanian Adults PHASE1 This is a randomized, double-blind, placebo-controlled trial to evaluate sa...
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Bagamoyo Research and Training Center of the Ifakara Health Institute
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Sanaria PfSPZ Challenge With Pyrimethamine or Chloroquine Chemoprophylaxis Vaccination (PfSPZ-CVac Approach): A Randomized Double Blind Placebo Controlled Phase I/II Trial to Determine Safety and Protective Efficacy Against Natural Plasmodium Falcipa... PHASE1 Background:
Malaria remains a major global health problem. Malaria is spre...
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Malaria Vaccine Center STTB/MRTC
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Dose Escalation, Randomized Controlled Trial to Evaluate the Safety, Immunogenicity and Efficacy of Intravenously Administered Attenuated Plasmodium Falciparum Sporozoite Vaccine (PfSPZ Vaccine) in Tanzanian Adults PHASE1 This trial will evaluate whether relatively non-immune populations in endem...
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Bagamoyo Research and Training Center, Ifakara Health Institute, Kingani Estate, PO Box 74
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Age De-escalation Safety Trial of PfSPZ-LARC2 Vaccine in Burkina Faso PHASE1 This is a first-in-humans randomized, double-blind, placebo-controlled, age...
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Groupe de Recherche Action en Santé (GRAS) / Unité de Recherche Clinique de Sabou
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Regimen Optimization Trial of PfSPZ Vaccine in Equatorial Guinea PHASE1 This is a phase 1, randomized regimen optimization study of PfSPZ Vaccine i...
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Baney Clinical Research Center
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A Study to Determine if New Types of Malaria Vaccines Are Safe, Effective and Lead to Immunity in Kenyan Adults PHASE2 This is a phase IIb clinical trial in malaria-exposed individuals to assess...
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KEMRI/Wellcome Trust Programme, Centre for Geographic Medicine Research - Coast
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